Publications

(Impact Factors 2010 in parenthesis)

Papers in press


Paar M, Jüngst C, Steiner NA, Magnes C, Sinner F, Kolb D, Lass A, Zimmermann R, Zumbusch A, Kohlwein SD, Wolinski H. Remodeling Of lipid droplets during lipolysis and growth in adipocytes. J Biol Chem, in press (Epub_ahead_of_print). (5.328)

Schernthaner M, Reisinger B, Wolinski H, Kohlwein SD, Trantina-Yates A, Fahrner M, Romanin C, Itani H, Stifter D, Leitinger G, Groschner K, Heitz J. 2012. Nanopatterned polymer substrates promote endothelial proliferation by initiation of beta-catenin transcriptional signaling. Acta Biomater, in press (Epub ahead of print). (4.824)

 

 
 
GOLD Publications 2012

Kumari M, Schoiswohl G, Chitraju C, Paar M, Cornaciu I, Ranrez AY, Wongsiriroj N, Nagy HM, Ivanova PT, Scott SA, Knittelfelder O, Rechberger GN, Birner-Gruenberger R, Eder S, Brown HA, Haemmerle G, Oberer M, Lass A, Kershaw EE, Zimmermann R, Zechner R. 2012. Adiponutrin Functions as a Nutritionally Regulated Lysophosphatidic Acid Acyltransferase. Cell Metab, 15(5):691-702. (18.207)

Zechner R, Zimmermann R, Eichmann TO, Kohlwein SD, Haemmerle G, Lass A, Madeo F. 2012. FAT SIGNALS-Lipases and Lipolysis in Lipid Metabolism and Signaling. Cell Metab, 15(3):279-291. (18.207)

Grall A, Guaguere E, Planchais S, Grond S, Bourrat E, Hausser I, Hitte C, Le Gallo M, Derbois C, Kim GJ, Lagoutte L, Degorce-Rubiales F, Radner FP, Thomas A, Küry S, Bensignor E, Fontaine J, Pin D, Zimmermann R, Zechner R, Lathrop M, Galibert F, Andre C, Fischer J. 2012. PNPLA1 mutations cause autosomal recessive congenital ichthyosis in golden retriever dogs and humans. Nat Genet, 44(2):140-147. (36.377)

Schreiber R, Taschler U, Preiss-Landl K, Wongsiriroj N, Zimmermann R, Lass A. 2012. Retinyl ester hydrolases and their roles in vitamin A homeostasis (Review). Biochim Biophys Acta,_1821(1):113-123. (5.084)

Schittmayer M, Birner-Gruenberger R. 2012. Lipolytic proteomics. Mass Spectrom Rev,_doi: 10.1002/mas.20355. (9.091)

Birner-Gruenberger R, Bickmeyer I, Lange J, Hehlert P, Hermetter A, Kollroser M, Rechberger GN, Kühnlein RP. 2012. Functional fat body proteomics and gene targeting reveal in vivo functions of Drosophila melanogaster alpha-Esterase-7. Insect Biochem Mol Biol, 42(3):220-229. (4.018)

Viertler M, Schittmayer M, Birner-Gruenberger R. 2012. Activity based subcellular resolution imaging of lipases. Bioorg Med Chem, 20(2):628-632. (2.978)

Aflaki E, Doddapattar P, Radovic B, Povoden S, Kolb D, Vujic N, Wegscheider M, Koefeler H, Hornemann T, Graier WF, Malli R, Madeo F, Kratky D. 2012. C16 ceramide is crucial for triacylglycerol-induced apoptosis in macrophages. Cell Death Dis, 3:e280. doi: 10.1038/cddis.2012.17.

Henry SA, Kohlwein SD, Carman GM. 2012. Metabolism and Regulation of Glycerolipids in the Yeast Saccharomyces cerevisiae. Genetics, 190(2):317-349. (4.087)

Wolinski H, Bredies K, Kohlwein SD. 2012. Quantitative imaging of lipid metabolism in yeast: from 4D analysis to high content screens of mutant libraries. Methods Cell Biol (invated), 108:345-365. (2.05)

Kloss-Brandstätter A, Erhart G, Lamina C, Meister B, Haun M, Coassin S, Seifert M, Klein-Franke A, Paulweber B, Kedenko L, Kollerits B, Swinkels DW, Vermeulen SH, Galesloot TE, Kronenberg F, Weiss G. 2012. Candidate Gene Sequencing of SLC11A2 and TMPRSS6 in a Family with Severe Anaemia: Common SNPs, Rare Haplotypes, No Causative Mutation. PLoS One, 7(4):e35015. (4.411)

Dastani Z, Hivert MF, Timpson N, Perry JR, Yuan X, Scott RA, Henneman P, Heid IM, Kizer JR, Lyytikäinen LP, Fuchsberger C, Tanaka T, Morris AP, Small K, Isaacs A, Beekman M, Coassin S, Lohman K, Qi L, Kanoni S, Pankow JS, Uh HW, Wu Y, Bidulescu A, Rasmussen-Torvik LJ, Greenwood CM, Ladouceur M, Grimsby J, Manning AK, Liu CT, Kooner J, Mooser VE, Vollenweider P, Kapur KA, Chambers J, Wareham NJ, Langenberg C, Frants R, Willems-Vandijk K, Oostra BA, Willems SM, Lamina C, Winkler TW, Psaty BM, Tracy RP, Brody J, Chen I, Viikari J, Kähönen M, Pramstaller PP, Evans DM, St Pourcain B, Sattar N, Wood AR, Bandinelli S, Carlson OD, Egan JM, Böhringer S, van Heemst D, Kedenko L, Kristiansson K, Nuotio ML, Loo BM, Harris T, Garcia M, Kanaya A, Haun M, Klopp N, Wichmann HE, Deloukas P, Katsareli E, Couper DJ, Duncan BB, Kloppenburg M, Adair LS, Borja JB; DIAGRAM+ Consortium; MAGIC Consortium; GLGC Investigators; MuTHER Consortium, Wilson JG, Musani S, Guo X, Johnson T, Semple R, Teslovich TM, Allison MA, Redline S, Buxbaum SG, Mohlke KL, Meulenbelt I, Ballantyne CM, Dedoussis GV, Hu FB, Liu Y, Paulweber B, Spector TD, Slagboom PE, Ferrucci L, Jula A, Perola M, Raitakari O, Florez JC, Salomaa V, Eriksson JG, Frayling TM, Hicks AA, Lehtimäki T, Smith GD, Siscovick DS, Kronenberg F, van Duijn C, Loos RJ, Waterworth DM, Meigs JB, Dupuis J, Richards JB. 2012. Novel Loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. PLoS Genet, 8(3):e1002607. (9.543)

Böger CA, Kronenberg F. 2012. How healthy are your vessels?-Check your urine! Atherosclerosis, 220(1):38-41. (4.086)

 

GOLD Publications 2011

Hakim-Weber R, Krogsdam AM, Jorgensen C, Fischer M, Prokesch A, Bogner-Strauss JG, Bornstein SR, Hansen JB, Madsen L, Kristiansen K, Trajanoski Z, Hackl H. 2011. Transcriptional regulatory program in wild-type and retinoblastoma gene-deficient mouse embryonic fibroblasts during adipocyte differentiation. BMC Res Notes, 4:157.

Hofer E, Laschober GT, Hackl M, Thallinger GG, Lepperdinger G, Grillari J, Jansen-Dürr P, Trajanoski Z. 2011. GiSAO.db: a database for ageing research. BMC Genomics, 12:262. (4.206)

Pabinger S, Rader R, Agren R, Nielsen J, Trajanoski Z. 2011. MEMOSys: Bioinformatics platform for genome-scale metabolic models. BMC Syst Biol, 5:20. (3.565)

Bennett KL, Funk M, Tschernutter M, Breitwieser FP, Planyavsky M, Ubaida Mohien C, Müller A, Trajanoski Z, Colinge J, Superti-Furga G, Schmidt-Erfurth U. 2011. Proteomic analysis of human cataract aqueous humour: Comparison of one-dimensional gel LCMS with two-dimensional LCMS of unlabelled and iTRAQ®-labelled specimens. J Proteomics, 74(2):151-166. (5.074)

Karbiener M, Neuhold C, Opriessnig P, Prokesch A, Bogner-Strauss JG, Scheideler M. 2011. MicroRNA-30c promotes human adipocyte differentiation and co-represses PAI-1 and ALK2. RNA_Biol,_8(5):_850-860. (5.597)

Pinent M, Prokesch A, Hackl H, Voshol PJ, Klatzer A, Walenta E, Kenner L, Trajanoski Z, Hoefler G, Bogner-Strauss JG. 2011. Adipose triglyceride lipase is involved in fat loss in JunB-deficient mice. Endocrinology, 152(7):2678-2689. (4.993)

Prokesch A, Bogner-Strauss JG, Hackl H, Rieder D, Neuhold C, Walenta E, Krogsdam A, Scheideler M, Papak C, Wong WC, Vinson C, Eisenhaber F, Trajanoski Z. 2011. Arxes: retrotransposed genes required for adipogenesis. Nucleic Acids Res, 39(8):3224-3239. (7.836)

Hörl G, Wagner A, Cole LK, Malli R, Reicher H, Kotzbeck P, Köfeler H, Höfler G, Frank S, Bogner-Strauss JG, Sattler W, Vance DE, Steyrer E. 2011. Sequential synthesis and methylation of phosphatidylethanolamine promote lipid droplet biosynthesis and stability in tissue culture and in vivo. J_Biol_Chem,_286(19):17338-17350. (5.328)

Taschler U, Radner FP, Heier C, Schreiber R, Schweiger M, Schoiswohl G, Preiss-Landl K, Jaeger D, Reiter B, Koefeler HC, Wojciechowski J, Theussl C, Penninger JM, Lass A, Haemmerle G, Zechner R, Zimmermann R. 2011. Monoglyceride lipase deficiency in mice impairs lipolysis and attenuates diet-induced insulin resistance. J Biol Chem, 286(20):17467-17477. (5.328)

Haemmerle G, Moustafa T, Woelkart G, Kotzbeck P, Büttner S, Schmidt A, van de Weijer T, Hesselink M, Kienesberger P, Zierler K, Schreiber R, Eichmann T, Kolb D, Schweiger M, Kumari M, Eder S, Schoiswohl G, Wongsiriroj N, Jäger D, Pollak N, Preiss-Landl K, Kolbe T, Rülicke T, Pieske B, Trauner M, Lass A, Zimmermann R, Hoefler G, Cinti S, Kershaw EE, Schrauwen P, Madeo F, Mayer B, Zechner R. 2011. ATGL-mediated fat catabolism regulates cardiac mitochondrial function via PPAR-α and PGC-1. Nat_Med,_17(9):1076-1085. (25.430)

Radner FP, Grond S, Lass A, Zechner R. 2011. Fat in the skin: triacylglycerol metabolism in keratinocytes and its role in the development of neutral lipid storage disease (Review). Dermatoendocrinol, 3(2):77-83.

Basantani MK, Sitnick MT, Cai L, Brenner DS, Gardner NP, Li JZ, Schoiswohl G, Yang K, Kumari M, Gross RW, Zechner R, Kershaw EE. 2011. Pnpla3/Adiponutrin deficiency in mice does not contribute to fatty liver disease or metabolic syndrome. J Lipid Res, 52(2):318-329. (6.115)

Das SK, Eder S, Schauer S, Diwoky C, Temmel H, Guertl B, Gorkiewicz G, Tamilarasan KP, Kumari P, Trauner M, Zimmermann R, Vesely P, Haemmerle G, Zechner R, Hoefler G. 2011. Adipose triglyceride lipase contributes to cancer-associated cachexia. Science, 333(6039):233-238. (31.377)

Aflaki E, Balenga NA, Luschnig-Schratl P, Wolinski H, Povoden S, Konya V, Bogner-Strauss JG, Kohlwein S-D, Heinemann A, Kratky D. 2011. Impaired Rho GTPase activation abrogates cell polarization and migration in macrophages with defective lipolysis. Cell Mol Life Sci, 68(23):3933-3947. (7.047)

Chandak PG, Obrowsky S, Radovic B, Doddapattar P, Aflaki E, Kratzer A, Doshi LS, Povoden S, Ahammer H, Hoefler G, Levak-Frank S, Kratky D. 2011. Lack of acyl-CoA:diacylglycerol acyltransferase 1 reduces intestinal cholesterol absorption and attenuates atherosclerosis in apolipoprotein E knockout mice. Biochim_Biophys Acta, 1811(12):1011-1020. (5.084)

Grunert T, Leitner NR, Marchetti-Deschmann M, Miller I, Wallner B, Radwan M, Vogl C, Kolbe T, Kratky D, Gemeiner M, Allmaier G, Müller M, Strobl B. 2011. A comparative proteome analysis links tyrosine kinase 2 (Tyk2) to the regulation of cellular glucose and lipid metabolism in response to poly(I:C). J_Proteomics, 74(12):2866-2880. (5.074)

Chennamsetty I, Claudel T, Kostner KM, Baghdasaryan A, Kratky D, Levak-Frank S, Frank S, Gonzalez FJ, Trauner M, Kostner GM. 2011. Farnesoid X receptor represses hepatic human APOA gene expression. J_Clin Invest, 121(9):3724-3734. (14.152)

Kratky D. 2011. Neutral cholesterol ester hydrolases in macrophages: still a matter of debate. Circ_Res, 108(10):e13. (9.504)

Patankar JV, Chandak PG, Obrowsky S, Pfeifer T, Diwoky C, Uellen A, Sattler W, Stollberger R, Hoefler G, Heinemann A, Battle M, Duncan S, Kratky D, Levak-Frank S. 2011. Loss of intestinal GATA4 prevents diet-induced obesity and promotes insulin sensitivity in mice. Am_J_Physiol_Endocrinol_Metab,_300(3):E478-488. (4.686)

Pfeifer T, Buchebner M, Chandak PG, Patankar J, Kratzer A, Obrowsky S, Rechberger GN, Kadam RS, Kompella UB, Kostner GM, Kratky D, Levak-Frank S. 2011. Synthetic LXR Agonist Suppresses Endogenous Cholesterol Biosynthesis and Efficiently Lowers Plasma Cholesterol. Curr_Pharm_Biotechnol,_12(2): 285-292. (3.455)

Aflaki E, Radovic B, Chandak PG, Kolb D, Eisenberg T, Ring J, Fertschai I, Wolinski W, Kohlwein SD, Zechner R, Levak-Frank S, Graier W, Malli R, Madeo F, Kratky D. 2011. Triacylglycerol accumulation activates the mitochondrial apoptosis pathway in macrophages. J Biol Chem, 286(9):7418–7428. (5.328)

Lammers B, Chandak PG, Aflaki E, Van Puijvelde GH, Radovic B, Hildebrand RB, Meurs I, Out R, Kuiper J, Van Berkel TJ, Kolb D, Haemmerle G, Zechner R, Levak-Frank S, Van Eck M, Kratky D. 2011. Macrophage adipose triglyceride lipase deficiency attenuates atherosclerotic lesion development in low-density lipoprotein receptor knockout mice. Arterioscler Thromb Vasc Biol, 31(1):67-73. (7.215)

Lass A, Zimmermann R, Oberer M, Zechner R. 2011. Lipolysis - a highly regulated multi-enzyme complex mediates the catabolism of cellular fat stores. Prog Lipid Res, 50(1):14-27. Review. (9.510)

Riegler B, Beseboeck C, Bauer R, Nimpf J, Schneider WJ. 2011. Enzymes involved in hepatic acylglycerol metabolism in the chicken. Biochem Biophys Res Comm, 406(2):257-261. (2.595)

Wolinski H, Kolb D, Hermann S, Koning RI, Kohlwein SD. 2011. A role for seipin in lipid droplet dynamics and inheritance in yeast. J Cell Sci, 124(Pt 22):3894-3904. (6.290)

Gaspar ML, Hofbauer H, Kohlwein SD, Henry SA. 2011. Coordination of storage lipid synthesis and membrane biogenesis: Evidence for cross-talk between triacylglycerol metabolism and phosphatidylinositol synthesis. J Biol Chem, 286(3):1696-1708. (5.328)

Cornaciu I, Boeszoermenyi A, Lindermuth H, Nagy HM, Cerk IK, Ebner C, Salzburger B, Gruber A, Schweiger M, Zechner R, Lass A, Zimmermann R, Oberer M. 2011. The Minimal Domain of Adipose Triglyceride Lipase (ATGL) Ranges until Leucine 254 and Can Be Activated and Inhibited by CGI-58 and G0S2, Respectively. PLoS ONE 6(10): e26349. (4.411)

Oberer M, Boeszoermenyi A, Nagy HM, Zechner R. 2011. Recent insights into the structure and function of CGI-58. Curr Opin Lipidol, 22(3):149-158. (6.636)

Lamina C, Coassin S, Illig T, Kronenberg F. 2011. Look beyond one's own nose: Combination of information from publicly available sources reveals an association of GATA4 polymorphisms with plasma triglycerides. Atherosclerosis, 219(2):698-703. (4.086)

Kloss-Brandstätter A, Pacher D, Schönherr S, Weissensteiner H, Binna R, Specht G, Kronenberg F. 2011. HaploGrep: a fast and reliable algorithm for automatic classification of mitochondrial DNA haplogroups. Hum Mutat, 32(1):25-32. (5.956)

Böger CA, Gorski M, Li M, Hoffmann MM, Huang C, Yang Q, Teumer A, Krane V, O'Seaghdha CM, Kutalik Z, Wichmann HE, Haak T, Boes E, Coassin S, Coresh J, Kollerits B, Haun M, Paulweber B, Köttgen A, Li G, Shlipak MG, Powe N, Hwang SJ, Dehghan A, Rivadeneira F, Uitterlinden A, Hofman A, Beckmann JS, Krämer BK, Witteman J, Bochud M, Siscovick D, Rettig R, Kronenberg F, Wanner C, Thadhani RI, Heid IM, Fox CS, Kao WH; The CKDGen Consortium. 2011. Association of eGFR-Related Loci Identified by GWAS with Incident CKD and ESRD. PLoS Genet, 7(9):e1002292. (9.543)

Suhre K, Shin SY, Petersen AK, Mohney RP, Meredith D, Wägele B, Altmaier E, Deloukas P, Erdmann J, Grundberg E, Hammond CJ, de Angelis MH, Kastenmüller G, Köttgen A, Kronenberg F, Mangino M, Meisinger C, Meitinger T, Mewes HW, Milburn MV, Prehn C, Raffler J, Ried JS, Römisch-Margl W, Samani NJ, Small KS, Wichmann HE, Zhai G, Illig T, Spector TD, Adamski J, Soranzo N, Gieger C. 2011. Human metabolic individuality in biomedical and pharmaceutical research. Nature, 477(7362):54-60. (36.104)

Mittelstrass K, Ried JS, Yu Z, Krumsiek J, Gieger C, Prehn C, Roemisch-Margl W, Polonikov A, Peters A, Theis FJ, Meitinger T, Kronenberg F, Weidinger S, Wichmann HE, Suhre K, Wang-Sattler R, Adamski J, Illig T. 2011. Discovery of sexual dimorphisms in metabolic and genetic biomarkers. PLoS Genet, 7(8):e1002215. (9.543)

Zabaneh D, Kumari M, Sandhu M, Wareham N, Wainwright N, Papamarkou T, Hopewell J, Clarke R, Li K, Palmen J, Talmud PJ, Kronenberg F, Lamina C, Summerer M, Paulweber B, Price J, Fowkes G, Stewart M, Drenos F, Shah S, Shah T, Casas JP, Kivimaki M, Whittaker J, Hingorani AD, Humphries SE. 2011. Meta analysis of candidate gene variants outside the LPA locus with Lp(a) plasma levels in 14,500 participants of six White European cohorts. Atherosclerosis, 217(2):447-451. (4.086)

 

GOLD Publications 2010

Mlecnik B, Sanchez-Cabo F, Charoentong P, Bindea G, Pages F, Berger A, Galon J, Trajanoski Z. 2010. Data integration and exploration for the identification of molecular mechanisms in tumor-immune cells interaction. BMC Genomics, 11 Suppl 1:S7. (4.206)

Laschober GT, Ruli D, Hofer E, Muck C, Carmona-Gutierrez D, Ring J, Hutter E, Ruckenstuhl C, Micutkova L, Brunauer R, Jamnig A, Trimmel D, Herndler-Brandstetter D, Brunner S, Zenzmaier C, Sampson N, Breitenbach M, Fröhlich KU, Grubeck-Loebenstein B, Berger P, Wieser M, Grillari-Voglauer R, Thallinger GG, Grillari J, Trajanoski Z, Madeo F, Lepperdinger G, Jansen-Dürr P. 2010. Identification of evolutionarily conserved genetic regulators of cellular aging. Aging Cell, 9(6):1084-1097. (7.148)

Hackl M, Brunner S, Fortschegger K, Schreiner C, Micutkova L, Mück C, Laschober GT, Lepperdinger G, Sampson N, Berger P, Herndler-Brandstetter D, Wieser M, Kühnel H, Strasser A, Rinnerthaler M, Breitenbach M, Mildner M, Eckhart L, Tschachler E, Trost A, Bauer JW, Papak C, Trajanoski Z, Scheideler M, Grillari-Voglauer R, Grubeck-Loebenstein B, Jansen-Dürr P, Grillari J. 2010. miR-17, miR-19b, miR-20a, and miR-106a are down-regulated in human aging. Aging Cell, 9(2):291-296. (7.148)

Bogner-Strauss JG, Prokesch A, Sanchez-Cabo F, Rieder D, Hackl H, Duszka K, Krogsdam A, Di Camillo B, Walenta E, Klatzer A, Lass A., Pinent M, Wong W-C, Eisenhaber F, Trajanoski Z. 2010. Reconstruction of gene association network reveals a transmembrane protein required for adipogenesis and targeted by PPARg. Cell Mol Life Sci, 67(23):4049-4064. (7.047)

Merkel O, Hamacher F, Laimer D, Sifft E, Trajanoski Z, Scheideler M, Egger G, Hassler MR, Thallinger C, Schmatz A, Thurner SD, Greil R and Kenner L. Identification of differential and functionally active miRNAs in both anaplastic lymphoma kinase (ALK)+ and ALK- anaplastic large-cell lymphoma. Proc_Natl_Acad_Sci_USA, 107(37):16228-16233. (9.771)

Plochberger B, Stockner T, Chiantia S, Brameshuber M, Weghuber J, Hermetter A, Schwille P, Schütz GJ. 2010. Cholesterol slows down the lateral mobility of an oxidized phospholipid in a supported lipid bilayer. Langmuir, 26(22):17322-17329. (4.269)

Schicher M, Morak M, Birner-Gruenberger R, Rechberger G, Kollroser M, Hermetter A. 2010. Functional proteomic analysis of lipases and esterases in cultured human adipocytes. J_Proteome_Res,_9(12):6334-6344. (5.460)

Radner FP, Streith IE, Schoiswohl G, Schweiger M, Kumari M, Eichmann TO, Rechberger G, Koefeler HC, Eder S, Schauer S, Theussl HC, Preiss-Landl K, Lass A, Zimmermann R, Hoefler G, Zechner R, Haemmerle G. 2010. Growth retardation, impaired triacylglycerol catabolism, hepatic steatosis, and lethal skin barrier defect in mice lacking comparative gene identification-58 (CGI-58). J Biol Chem, 285(10):7300-7311. (5.328)

Schoiswohl G, Schweiger M, Schreiber R, Gorkiewicz G, Preiss-Landl K, Taschler U, Zierler KA, Radner FP, Eichmann TO, Kienesberger PC, Eder S, Lass A, Haemmerle G, Alsted TJ, Kiens B, Hoefler G, Zechner R, Zimmermann R. 2010. Adipose triglyceride lipase plays a key role in the supply of the working muscle with fatty acids. J Lipid Res, 51(3):490-499. (6.115)

Heier C, Taschler U, Rengachari S, Oberer M, Wolinski H, Natter K, Kohlwein SD, Leber R, Zimmermann R. 2010. Identification of Yju3p and Dga1p as monoacylglycerol metabolizing enzymes in the yeast S. cerevisae. BBA-Mol Cell Biol Lipids, 1801(9):1063-1071. (5.084)

Gruber A, Cornaciu I, Lass A, Schweiger M, Schoiswohl G, Wolinski H, Kohlwein SD, Zechner R, Zimmermann R, Oberer M. 2010. The N-terminal region of CGI-58 is important for lipid droplet binding and activation of adipose triglyceride lipase. J Biol Chem, 285(16):12289-12298. (5.328)

Chandak PG, Radovic B, Aflaki E, Kolb D, Buchebner M, Fröhlich E, Magnes C, Sinner F, Haemmerle G, Zechner R, Tabas I, Levak-Frank S, Kratky D. 2010. Efficient phagocytosis requires triacylglycerol hydrolysis by adipose triglyceride lipase. J Biol Chem, 285(26):20192-20201. (5.328)

Buchebner M, Pfeifer T, Rathke N, Chandak PG, Lass A, Schreiber R, Kratzer A, Zimmermann R, Sattler W, Koefeler H, Fröhlich E, Kostner GM, Birner-Gruenberger R, Chiang KP, Haemmerle G, Zechner R, Levak-Frank S, Cravatt B, Kratky D. 2010. Cholesteryl ester hydrolase activity is abolished in HSL-/- macrophages but unchanged in macrophages lacking KIAA1363. J Lipid Res, 51(10):2896-2908. (6.115)

Kohlwein SD. 2010. Triacylglycerol homeostasis: insights from yeast. Invited review. J_Biol_Chem, 285(21):15663-15667. (5.328)

Kohlwein SD. 2010. Obese and anorexic yeasts: experimental models to understand the metabolic syndrome and lipotoxicity. Review. BBA - Mol Cell Biol Lipids, 1801(3):222-229. (5.084)

Deng Y, Zakaria AA, Ng MML, Kohlwein SD. 2010. Do viruses subvert cholesterol homeostasis to induce host cubic membranes? Trends Cell Biol (invited review), 20(7):371-379. (12.140)

Weißensteiner H*, Schönherr S*, Specht G, Kronenberg F, Brandstätter A (*equal contribution). 2010. eCOMPAGT integrates mtDNA: import, validation and export of mitochondrial DNA profiles for population genetics, tumour dynamics and genotype-phenotype association studies. BMC_Bioinformatics,_11:122. (3.029)

Forer L, Schönherr S, Weissensteiner H, Haider F, Kluckner T, Gieger C, Wichmann HE, Specht G, Kronenberg F, Brandstätter A. 2010. CONAN: Copy Number Variation Analysis Software for Genome-Wide Association Studies. BMC Bioinformatics, 11:318. (3.428)

Willeit P, Willeit J, Brandstätter A, Ehrlenbach S, Mayr A, Gasperi A, Weger S, Oberhollenzer F, Reindl M, Kronenberg F, Kiechl S. 2010. Cellular aging reflected by leukocyte telomere length predicts advanced atherosclerosis and cardiovascular disease risk. Arterioscler Thromb Vasc Biol, 30(8):1649-1656. (7.215)

Lamina C, Küchenhoff H, Chang-Claude J, Paulweber B, Wichmann HE, Illig T, Hoehe MR, Kronenberg F, Heid IM. 2010. Haplotype misclassification resulting from statistical reconstruction and genotype error, and its impact on association estimates. Ann Hum Genet, 74(5):452-462. (2.604)

Heid IM, Teslovich TM, Musunuru K, Smith AV, [etc.] Kronenberg F, et al. 2010. Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. Nature Genet, 42(11):949-960. (36.377)

Suhre K, Meisinger C, Döring A, Altmaier E, Belcredi P, Gieger C, Chang D, Milburn MV, Gall WE, Weinberger KM, Mewes HW, Hrabe de Angelis M, Wichmann HE, Kronenberg F, Adamski J, Illig T. 2010. Metabolic footprint of diabetes: a multiplatform metabolomics study in an epidemiological setting. PLoS_One,_5(11):e13953. (4.411)

Kronenberg F. 2010. Association of bilirubin with cardiovascular outcomes. More hype than substance? Circ Cardiovasc Genet, 3(4):308-310. (4.043)

Coassin S, Schweiger M, Kloss-Brandstätter A, Lamina C, Haun M, Erhart G, Paulweber B, Rahman Y, Olpin S, Wolinski H, Cornaciu I, Zechner R, Zimmermann R, Kronenberg F. 2010. Investigation and functional characterization of rare genetic variants in the adipose triglyceride lipase in a large healthy working population. PLoS Genet, 6(12):e1001239. (9.543)

Coassin S, Brandstätter A, Kronenberg F. 2010. Lost in the space of bioinformatic tools: a constantly updated survival guide for genetic epidemiology. The GenEpi Toolbox. Atherosclerosis,_209(2):321-335. Review. (4.086)

Koettgen A, Pattaro C, Böger CA, [etc.], Kronenberg F, [etc.], Brandstätter A, Kollerits B, [etc.], Heid IM, Fox CS. 2010. New loci associated with kidney function and chronic kidney disease: The CKDGen Consortium. Nature Genet, 42(5): 376-384. (36.377)

Brandstätter A, Lamina C, Kiechl S, Hunt SC, Coassin S, Paulweber B, Kramer F, Summerer M, Willeit J, Kedenko L, Adams TD, Kronenberg F. 2010. Sex and age interaction with genetic association of atherogenic uric acid concentrations. Atherosclerosis, 210(2):474-478. (4.086)

Kollerits B, Coassin S, Kiechl S, Hunt SC, Paulweber B, Willeit J, Brandstaetter A, Adams TD, Kronenberg F. 2010. A common variant in the adiponutrin gene influences liver enzyme levels. J Med Genet, 47(2):116-119 (7.037) Pubmed

Heid IM, Henneman P, Hicks A, Coassin S, Winkler T, Aulchenko YS, Fuchsberger C, Song K, Hivert MF, Waterworth DM, Timpson NJ, Richards JB, Perry JRB, Tanaka T, Amin N, Kollerits B, Pichler I, Oostra BA, Thorand B, Frants RR, Illig T, Dupuis J, Glaser B, Spector T, Guralnik J, Egan JM, Florez JC, Evans DM, Soranzo N, Bandinelli S, Carlson OD, Frayling TM, Burling K, Davey SG, Mooser V, Ferrucci L, Meigs JB, Vollenweider P, Van Dijk KW, Pramstaller P*, Kronenberg F, Van Duijn CM. 2010. Clear detection of ADIPOQ locus as the major gene for plasma adiponectin: results of genome-wide association analyses including 4659 European individuals. Atherosclerosis, 208(2):412-420. (4.086)

Linsel-Nitschke P, Heeren J, Aherrahrou Z, Bruse P, Gieger C, Illig T, Prokisch H, Heim K, Doering A, Peters A, Meitinger T, Wichmann HE, Hinney A, Reinehr T, Roth A, Ortlepp JR, Soufi M, Sattler AM, Schaefer J, Stark K, Hengstenberg C, Schaefer A, Schreiber S, Kronenberg F, Samani NJ, Schunkert H, Erdmann J. 2010. Genetic variation at chromosome 1p13.3 affects sortilin mRNA expression, cellular LDL uptake and serum LDL levels which translates to the risk of coronary artery disease. Atherosclerosis, 208(1):183-189. (4.086)

Spanaus K-S, Kollerits B, Ritz E, Hersberger M, Kronenberg F, von Eckardstein A. 2010. Serum markers in chronic kidney disease: diagnostic performance of serum creatinine, cystatin C, and beta-trace protein and prediction of progression of primary non-diabetic chronic kidney disease. Clin Chem, 56(5):740-749. (6.886)

Illig T, Gieger C, Zhai G, Roemisch-Margl W, Wang-Sattler R, Prehn C, Altmaier E, Kastenmueller G, Kato BS, Soranzo N, Mewes HW, Meitinger T, Hrabe de Angelis M, Kronenberg F, Wichmann HE, Spector TD, Adamski J, Suhre K. 2010. A genome-wide perspective of genetic variation in human metabolism. Nature_Genetics, 42(2):137-141. (36.377)

 

GOLD Publications 2009

(Impact Factors 2009 in parenthesis)

Schicher M, Kollroser M, Hermetter A. 2009. Mapping the lipolytic proteome of adipose tissue using fluorescent suicide inhibitors. Methods Mol Biol ;579:497-511 (not listed) Pubmed

Morak M, Schmidinger H, Krempl P, Rechberger G, Kollroser M, Birner-Gruenberger R and Hermetter A. 2009. Differential activity-based gel electrophoresis (DABGE) for comparative analysis of lipolytic and esterolytic activities. J Lipid Res, 50(7):1281-1292 (4.409) Pubmed

Schittmayer M, Birner-Gruenberger R. 2009. Functional proteomics in lipid research: Lipases, lipid droplets and lipoproteins. J Proteomics, 72(6):1006-1018 (5.684) Pubmed

Kratzer A, Buchebner M, Pfeifer T, Becker TM, Uray G, Ebner B, Rathke N, Ahammer H, Trauner M, Hoefler G, Levak-Frank S, Kostner GM, Kratky D. 2009. Synthetic LXR agonist attenuates plaque formation and reduces plasma triglycerides in apoE-deficient mice without inducing liver steatosis. J Lipid Res, 50(2):312-326 (4.409)

Guertl B, Kratky D, Guelly C, Zhang L, Gorkiewicz G, Das SK, Tamilarasan KP, Hoefler G. 2009. Apoptosis and fibrosis are early features of heart failure in an animal model of metabolic cardiomyopathy. Int J Exp Pathol. 90(3):338-46

Schweiger M, Lass A, Zimmermann R, Eichmann TO, Zechner R. 2009. Neutral lipid storage disease: genetic disorders caused by mutations in adipose triglyceride lipase/PNPLA2 or CGI-58/ABH5. Review. Am J Physiol Endocrinol Metab, 297(2):E289-E296. (3.855) Pubmed

Riederer M, Erwa W, Zimmermann R, Frank S, Zechner R. 2009. Adipose tissue as a source of nicotinamide N-methyltransferase and homocysteine. Atherosclerosis, 204(2):412-417 (4.601) Pubmed

Zechner R, Kienesberger PC, Haemmerle G, Zimmermann R, Lass A. 2009. Adipose triglyceride lipase and the lipolytic catabolism of cellular fat stores. Review. J Lipid Res, 50(1):3-21 (4.409)

Zimmermann R, Lass A, Haemmerle G, Zechner R. 2009. Fate of fat: The role of adipose triglyceride lipase in lipolysis. Biochim Biophys Acta, 1791(6):494-500 (4.564)

Schreiber R, Taschler U, Wolinski H, Seper A, Tamegger SN, Graf M, Kohlwein SD, Haemmerle G, Zimmermann R, Zechner R, Lass A. 2009. Esterase 22 and beta-glucuronidase hydrolyze retinoids in mouse liver. J Lipid Res, 50(12):2514-2523 (4.409) Pubmed

Kienesberger PC, Lee D, Pulinilkunnil T, Brenner DS, Cai L, Magnes C, Koefeler HC, Streith IE, Rechberger GN, Haemmerle G, Flier JS, Zechner R, Kim YB, Kershaw EE. 2009. Adipose triglyceride lipase deficiency causes tissue-specific changes in insulin signaling. J Biol Chem, 284(44):30218-30229 (5.520) Pubmed

Saarela J, Metso J, Schneider WJ, Jauhiainen M. 2009. Avian phospholipid transfer protein causes HDL conversion without affecting cholesterol efflux from macrophages. BBA – Mol Cell Biol Lipids, 1791:781-789 (4.564) Pubmed

Schneider WJ. 2009. Receptor-mediated mechanisms in ovarian follicle and oocyte development. Review. Gen Comp Endocr, 163:18-23 (2.654) Pubmed

Petschnigg J, Wolinski H, Kolb D, Zellnig G, Kurat CF, Natter K, Kohlwein SD. 2009. Good fat - essential cellular requirements for triacylglycerol synthesis to maintain membrane homeostasis in yeast. J Biol Chem, 284(45):30981-30993 (5.520) Pubmed

Wolinski H, Natter K, Kohlwein SD. 2009. The fidgety yeast: focus on high-resolution live yeast cell microscopy. In:Methods in Molecular Biology, I. Stagljar, ed. Humana Press, volume 548, pp 75-99.

Kurat CF, Wolinski H, Petschnigg J, Kaluarachchi S, Andrews B, Natter K, Kohlwein SD. 2009. Cdk1/Cdc28-dependent activation of the major triacylglycerol lipase Tgl4 in yeast links lipolysis to cell cycle progression. Mol Cell, 33:53-63 (12.903) More

Wolinski H, Petrovic U, Mattiazzi M, Petschnigg J, Heise B, Natter K, Kohlwein SD. 2009. Imaging-based live cell yeast screen identifies novel factors involved in peroxisome assembly. J Proteome Res, 8(1):20-27 (5.684)

Lin JP, Schwaiger JP, Cupples LA, O'Donnell CJ, Zheng G, Schoenborn V, Hunt SC, Joo J, Kronenberg F. 2009. Conditional linkage and genome-wide association studies identify UGT1A1 as a major gene for anti-atherogenic serum bilirubin levels-The Framingham Heart Study. Atherosclerosis, 206(1):228-233 (4.601) Pubmed

Schoenherr S, Weissensteiner H, Coassin S, Specht G, Kronenberg F, Brandstaetter A. 2009. eCOMPAGT -- efficient combination and management of phenotypes and genotypes for genetic epidemiology. BMC Bioinformatics 11;10:139 (3.781)

N'Diaye M, Le Ferrec E, Kronenberg F, Dieplinger H, Le Vee M, Fardel O. 2009. TNFalpha- and NF-kappaB-dependent induction of the chemokine CCL1 in human macrophages exposed to the atherogenic lipoprotein(a). Life Sci 84(13-14):451-7 (2.583)

Hersberger M, Mueller M, Marti-Jaun J, Heid IM, Coassin S, Young TF, Waechter V, Hengstenberg C, Meisinger C, Peters A, Koenig W, Holmer S, Schunkert H, Klopp N, Kronenberg F, Illig T. 2009. No association of two functional polymorphisms in human ALOX15 with myocardial infarction. Atherosclerosis 205(1):192-6 (4.601)

Aulchenko YS, Ripatti S, Lindqvist I, Boomsma D, Heid IM, Pramstaller PP, Penninx BW, Janssens AC, Wilson JF, Spector T, Martin NG, Pedersen NL, Kyvik KO, Kaprio J, Hofman A, Freimer NB, Jarvelin MR, Gyllensten U, Campbell H, Rudan I, Johansson A, Marroni F, Hayward C, Vitart V, Jonasson I, Pattaro C, Wright A, Hastie N, Pichler I, Hicks AA, Falchi M, Willemsen G, Hottenga JJ, de Geus EJ, Montgomery GW, Whitfield J, Magnusson P, Saharinen J, Perola M, Silander K, Isaacs A, Sijbrands EJ, Uitterlinden AG, Witteman JC, Oostra BA, Elliott P, Ruokonen A, Sabatti C, Gieger C, Meitinger T, Kronenberg F, Doering A, Wichmann HE, Smit JH, McCarthy MI, van Duijn CM, Peltonen L; ENGAGE Consortium. 2009. Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts. Nat Genet. 41(1):47-55 (30.259)

Boes E, Coassin S, Kollerits B, Heid IM, Kronenberg F. 2009. Genetic-epidemiological evidence on genes associated with HDL cholesterol levels: a systematic in-depth review. Exp Gerontol. 44(3):136-60 (3.283)

Kollerits B, Coassin S, Beckmann ND, Teumer A, Kiechl S, Doering A, Kavousi M, Hunt SC, Lamina C, Paulweber B, Kutalik Z, Nauck M, Van Duijn CM, Heid IM, Willeit J, Brandstaetter A, Adams TD, Mooser V, Aulchenko YS, Voelzke H, Kronenberg F. 2009. Genetic evidence for a role of adiponutrin in the metabolism of apolipoprotein B-containing lipoproteins. Hum Mol Genet, 18:4669-4676 (7.249) Pubmed

Brandstaetter A, Lingenhel A, Zwiauer K, Strobl W, Kronenberg F. 2009. Decrease of Lp(a) during weight reduction in obese children is modified by the apo(a) kringle-IV copy number variation. Int J Obesity, 33:1136-1142 (3.640) Pubmed

Ehrlenbach S, Willeit P, Kiechl S, Willeit J, Reindl M, Schanda K, Kronenberg F, Brandstaetter A. 2009. Influences on the reduction of relative telomere length over ten years in the population-based Bruneck Study: introduction of a well-controlled high-throughput assay. Int J Epidemiol, 38:1725-1734 (5.838) Pubmed

Heid IM, Huth C, Loos RJF, Kronenberg F, Adamkova V, Anand SS, Ardlie K, Biebermann H, Bjerregaard P, Boeing H, Bouchard C, Ciullo M, Cooper JA, Corella D, Dina C, Engert JC, Fisher E, Frances F, Froguel P, Hebebrand J, Hegele RA, Hinney A, Hoehe MR, Hu FB, Hubacek JA, Humphries SE, Hunt SC, Illig T, Jarvelin MR, Kaakinen M, Kollerits B, Krude H, Kumar J, Lange LA, Langer B, Li S, Luchner A, Lyon HN, Meyre D, Mohlke KL, Mooser V, Nebel A, Nguyen TT, Paulweber B, Perusse L, Qi L, Rankinen T, Rosskopf D, Schreiber S, Sengupta S, Sorice R, Suk A, Thorleifsson G, Thorsteinsdottir U, Voelzke H, Vimaleswaran KS, Wareham NJ, Waterworth D, Yusuf S, Lindgren C, McCarthy MI, Lange C, Hirschhorn JN, Laird N, Wichmann HE. 2009. Meta-analysis of the INSIG2 association with obesity including 74,345 individuals: does heterogeneity of estimates relate to study design? PLoS Genetics, 5: e1000694 (8.883)

Kronenberg F. 2009. Emerging risk factors and markers of chronic kidney disease progression. Review. Nat Rev Nephrol, 5:677-689 (5.594)

Felt U, Fochler M. and Winkler P. 2009. Coming to Terms with Biomedical Technologies in Different Technopolitical Cultures. A Comparative Analysis of Focus Groups on Organ Transplantation and Genetic Testing in Austria, France, and the Netherlands. Science, Technology, & Human Values, OnlineFirst, October 27. (Social science citation index, SSCI 1.926)

Felt U, Bister M, Strassnig M, Wagner U. 2009. Refusing the information paradigm. Informed consent, medical research, and patient participation; Health: an interdisciplinary journal for the Social Study of Health, Illness and Medicine, 13/1: 87-106. (SSCI 1.080)

Felt U, Fochler M, Mueller A, Strassnig M. 2009. Unruly ethics - On the difficulties of a bottom-up approach to ethics in the field of genomics. Public Underst Sci, 18(3): 354-371. (SSCI 1.286)

 

GOLD2 Publications (2008-2006)

Pinent M, Hackl H, Burkard TR, Prokesch A, Paar C, Scheideler M, Golob N, Haemmerle G, Zechner R, Trajanoski Z, Strauss JG. 2008. Differential transcriptional modulation of biological processes in adipocyte triglyceride lipase and hormone-sensitive lipase deficient mice. Genomics, 92(1):26-32 (3.075)

Scheideler M, Elabd C, Zaragosi, LE, Chiellini C, Yadav S, Duszka K, Hackl H, Sanchez-Cabo F, Friedl G, Papak C, Prokesch A, Windhager R, Ailhaud G, Dani C, Amri EZ, Trajanoski Z. 2008. Comparative transciptomics of human multipotent stem cells during adipogenesis and osteoblastogenesis. BMC Genomics, 9:340. (4.128)

Chiellini C, Grenningloh G, Cochet O, Scheideler M, Trajanoski Z, Ailhaud G, Dani C, E-Z Amri. 2008. Stathmin-like 2, a developmentally-associated neuronal marker, is expressed and modulated during osteogenesis of human mesenchymal stem cells. Biochem Biophys Res Commun, 374(1):64-8 (2.648)

Elabd C, Basillais A, Beaupied H, Breuil V, Wagner N, Scheideler M, Zaragosi LE, Massiera F, Lemichez E, Trajanoski Z, Carle GF, Euller-Ziegler L, Ailhaud G, Benhamou CL, Dani C, Amri EZ. 2008. Oxytocin modulates psteoblast/adipocyte balance. Stem cells, 26(9):2399-407 (7.741)

Merkel O, Heyder C, Asslaber D, Hamacher F, Holler C, Stoecher M, Scheideler M, Paar C, Prokesch A, Trajanoski Z, Tinhofer I, Greil R. 2008. Arsenic trioxide induces apoptosis preferentially in B-CLL cells of patients with unfavourable prognostic factors including del17p13. J Mol Med, 86:541-552 (4.370)

Jo-Anne M. Rasmussen, Albin Hermetter. 2008. Chemical synthesis of fluorescent glycero- and sphingolipids. Prog Lipid Res 47:436–460

Schweiger M, Schoiswohl G, Lass A, Radner F, Haemmerle G, Malli R, Graier W, Cornaciu I, Oberer M, Fischer J, Zechner R, Zimmermann R. 2008. The C-terminal region of adipose triglyceride lipase affects enzyme activity and lipid droplet binding. J Biol Chem, 283:17211-17220 (5.520)

Kienesberger PC, Lass A, Preiss-Landl K, Wolinski H, Kohlwein SD, Zimmermann R, Zechner R. 2008. Identification of an insulin-regulated lysophospholipase with homology to neuropathy target esterase. J Biol Chem, 283:5908-5917 (5.520)

Wolinski H and Kohlwein SD. 2008. Microscopic analysis of lipid droplet metabolism and dynamics in yeast. Methods Mol Biol, 457:151-163 Pubmed

Zanghellini J, Natter K, Jungreuthmayer C, Thalhammer A, Kurat C, Gogg-Fassolter G, Kohlwein SD, von Gruenberg HH. 2008. Quantitative modelling of triacylglycerol homeostasis in yeast - metabolic requirement for lipolysis to promote membrane lipid synthesis and cellular growth. FEBS J, 275(22): 5552-5563 (3.264)

Kohlwein SD. 2008. Von fettleibigen und mageren Hefezellen: mikroskopische Einblicke in den zellulaeren Fettstoffwechsel. BIOforum, 2/2008, 021-023.

Dorfmeister B, Zeng WW, Dichlberger A, Nilsson SK, Schaap FG, Hubacek JA, Merkel M, Cooper JA, Lookene A, Putt W, Whittall R, Lee PJ, Lins L, Delsaux N, Nierman M, Kuivenhoven JA, Kastelein JJP, Vrablik M, Olivecrona G, Schneider WJ, Heeren, Humphries SE, Talmud PJ. 2008. Effects of six APOA5 mutations, associated with severe hypertriglyceridemia, on Lipoprotein Lipase activity and receptor binding in vitro. Arterioscler Thromb Vasc Biol, 28(10):1866-71 (6.858)

Saarela J, Jung G, Hermann M, Nimpf J, Schneider WJ. 2008. The patatin-like lipase family in Gallus gallus. BMC Genomics, 9:28 (4.128)

Lasky-Su J, Lyon HN, Emilsson V, Thorleifsson G, Thorsteinsdottir U, Stefansson K, Lazarus R, Klanderman B, Raby BA, Soto-Quiros ME, Avila L, Silverman EK, Celedon JC, Weiss ST, Heid IM, Kronenberg F, Vollmert C, Illig T, Wichmann HE, Fox CS, Levy D, O'Donnell CJ, Laird N, Ding X, McQueen M, Molony C, Schadt E, Butler J, Ardlie K, Hirschhorn J, Papoutsakis C, Dedoussis G, Lange C. 2008. SLC2A9 influences uric acid concentrations with pronounced sex-specific effects. Am J Hum Genet, 82(4):849-858 (10.153)

Doering A, Gieger C, Mehta D, Gohlke H, Prokisch H, Coassin S, Fischer G, Henke K, Klopp N, Kronenberg F, Paulweber B, Pfeufer A, Rosskopf D, Voelzke H, Illig T, Meitinger T, Wichmann HE, Meisinger C. 2008. SLC2A9 influences uric acid concentrations with pronounced sex-specific effects. Nature Genetics, 40:430-436 (30.259)

Boes E, Kollerits B, Heid IM, Hunt SC, Pichler M, Paulweber B, Coassin S, Adams TD, Hopkins PN, Lingenhel A, Wagner SA, Kronenberg F. 2008. INSIG2 polymorphism is neither associated with body mass index nor with phenotypes of lipoprotein metabolism. Obesity (Silver Spring), 16:827-833 (2.762)

Heid IM, Lamina C, Kuechenhoff H, Fischer G, Klopp N, Kolz M, Grallert H, Vollmert C, Wagner S, Huth C, Mueller J, Hunt SC, Peters A, Paulweber B, Wichmann HE, Kronenberg F, Illig T. 2008. Estimating the SNP genotyping misclassification from routine double measurements in a large epidemiological sample. Am J Epidemiol, 168(8):878-89. (5.454)

Pichler M, Kollerits B, Heid IM, Hunt SC, Adams TD, Hopkins PN, Kronenberg F. 2008. Association of the melanocortin-4 receptor V103I polymorphism with dietary intake in severely obese individuals, manuscript submitted. Am J Clin Nutrition, 47(6):436-60. (6.740)

Ye S, Willeit J, Kronenberg F, Xu Q, Kiechl S. 2008. Association of genetic variation on chromosome 9p21 with susceptibility and progression of atherosclerosis - a population-based, prospective study. J Am Coll Cardiol, 52(5):378-84 (11.438)

Brandstaetter A, Kiechl S, Kollerits B, Hunt SC, Heid IM, Coassin S, Willeit J, Adams TD, Illig T, Hopkins PN, Kronenberg F. 2008. The gender-specific association of the putative fructose transporter SLC2A9 variants with uric acid levels is modified by BMI. Diabetes Care, 31(8):1662-1667 (7.349)

Mueller AM, Doering A, Kuechenhoff H, Lamina C, Malzahn D, Bickeboeller H, Vollmert C, Klopp N, Meisinger C, Heinrich J, Kronenberg F, Wichmann HE, Heid IM. 2008. Quantifying the contribution of genetic variants for survival phenotypes. Genet Epidemiol, 32(6):574-585 (2.203)

Rantner B, Kollerits B, Anderwald-Stadler M, Klein-Weigel P, Gruber I, Gehringer A, Haak M, Schnapka-Koepf M, Fraedrich G, Kronenberg F. 2008. Association between the UGT1A1 TA-repeat polymorphism and bilirubin concentrations in patients with intermittent claudication: results from the CAVASIC Study. Clin Chem, 54(5):851-857 (5.579)

Heid IM, Vollmert C, Kronenberg F, Huth C, Ankerst D, Luchner A, Hinney A, Broenner G, Wichmann HE, Illig T, Doering A, Hebebrand J. 2008. Association of the MC4R V103I polymorphism with the metabolic syndrome: the KORA Study. Obesity, 16:369-376 Pubmed (2.762)

Gieger C, Geistlinger L, Altmaier E, Hrabe de Angelis M, Kronenberg F, Meitinger T, Mewes HW, Wichmann HE, Weinberger KM, Adamski J, Illig T, Suhre K. 2008. Genetics meets metabolomics: a genome-wide association study of metabolite profiles in human serum. PLoS Genet. 4(11):e1000282 (8.883)

Boes E, Coassin S, Kollerits B, Heid IM, Kronenberg F. 2008. Genetic-epidemiological evidence on genes associated with HDL cholesterol levels: a systematic in-depth review. Exp Gerontol 44(3):136-60 (3.283)

Coassin S, Brandstaetter A, Kronenberg F. 2008. An optimized procedure for the design and evaluation of Ecotilling assays. BMC Genomics 30;9:510 (4.128)

Felt U and Fochler M. 2008. The Bottom-Up Meanings of the Concept of Public Participation in Science and Technology. Science & Public Policy, 35(7).

Felt, U, Fochler, M, Mager, A, Winkler, P. 2008. Visions and versions of governing biomedicine. Narratives on power structures, decision-making and public participation in the field of biomedical technology in the Austrian context. Social Studies of Science, Vol. 38 (2):233-255.

Kulterer B, Friedl G, Jandrositz A, Sanchez-Cabo F, Prokesch A, Paar C, Scheideler M, Windhager R, Preisegger KH, Trajanoski Z. 2007. Gene expression profiling of human mesenchymal stem cells derived from bone marrow during expansion and osteoblast differentiation. BMC Genomics, 8:70 (4.128)

Mueller WG, Rieder D, Karpova TS, John S, Trajanoski Z, McNally JG. 2007. Organization of chromatin and histone modifications at a transcription site. J Cell Biol, 177:957-967. (9.120)

Hartler J, Thallinger GG, Stocker G, Sturn A, Burkard TR, Koerner E, Rader R, Schmidt A, Mechtler K, Trajanoski Z. 2007. MASPECTRAS: a platform for management and analysis of proteomics LC-MS/MS data. BMC Bioinformatics, 8:197. (3.781)

Birner-Gruenberger R, Hermetter A. 2007. Activity-based proteomics of lipolytic enzymes. Curr Drug Discov
Technol
, 4:1-11, 2007. Review

McGovern MM, Elles R, Beretta I, Somerville MJ, Hoefler G, Keinanen M, Barton D, Carson N, Dequeker E, Brdicka R, Blazkova A, Ayme S, Schnieders B, Muller CR, Dalen V, Martinez AA, Kristoffersson U, Ozguc M, Mueller H, Boone J, Lubin IM, Sequeiros J, Taruscio D, Williamson B, Mainland L, Yoshikura H, Ronchi E. 2007. Report of an international survey of molecular genetic testing laboratories. Community Genet, 10:123-131 (1.403)

Kohlwein SD, Petschnigg J. 2007. Lipid-induced Cell Dysfunction and Cell Death: Lessons from Yeast. Curr Hypertens Rep, 455-461 (1.885)

Mayr JA, Merkel O, Kohlwein SD, Gebhardt BR, Boehles H, Foetschl U, Koch J, Jaksch M, Lochmueller H, Horvath R, Freisinger P, Sperl W. 2007. Mitochondrial phosphate-carrier deficiency: a novel disorder of oxidative phosphorylation. Am J Hum Genet, 80(3):478-84 (10.153)

Tehlivets O, Scheuringer K, Kohlwein SD. 2007.Fatty acid synthesis and elongation in yeast. Review. Biochim Biophys Acta, 1771(3):255-270 (4.564)

Schneider WJ. 2007. Low density lipoprotein receptor relatives in chicken ovarian follicle and oocyte development. Cytogenet Genome Res, 117:248-255

Schoenborn V, Gohlke H, Heid IM, Illig T, Utermann G, Kronenberg F. 2007. Sample selection algorithm to improve quality of genotyping from plasma-derived DNA: to separate the wheat from the chaff. Human Mutation, 28:1141-1149 (7.033)

Kollerits B, Fliser D, Heid IM, Ritz E, Kronenberg F, for the MMKD Study Group. 2007. Gender-specific association of adiponectin as a predictor of progression of chronic kidney disease: The Mild to Moderate Kidney Disease (MMKD) Study. Kidney Int, 71:1279-1286 Pubmed (6.418)

Grallert H, Sedlmeier EM, Huth C, Kolz M, Heid IM, Meisinger C, Herder C, Strassburger K, Gehringer A, Haak M, Giani G, Kronenberg F, Wichmann HE, Adamski J, Paulweber B, Illig T, Rathmann W. 2007. APOA5 variants and metabolic syndrome in Caucasians. J Lipid Res, 48:2614-2621 (4.409)

Broedl UC, Schachinger V, Lingenhel A, Lehrke M, Stark R, Seibold F, Goeke B, Kronenberg F, Parhofer KG, Konrad-Zerna A. 2007. Apolipoprotein A-IV is an independent predictor of disease activity in patients with inflammatory bowel disease. Inflammatory Bowel Disease, 13:391-397 (4.975)

Kwan BCH, Kronenberg F, Beddhu S, Cheung AK. 2007. Lipoprotein metabolism and lipid management in chronic kidney disease. J Am Soc Nephrol, 18:1246-1261 (7.505)

Fliser D*, Kollerits B*, Neyer U, Ankerst DK, Lhotta K, Lingenhel A, Ritz E, Kronenberg F, for the MMKD Study Group (* contributed equally). 2007. Fibroblast Growth Factor 23 (FGF23) predicts progression of chronic kidney disease: The Mild to Moderate Kidney Disease (MMKD) Study. J Am Soc Nephrol, 18:2600-2608 (7.505)

Bordeleau ME, Mori A, Oberer M, Lindqvist L, Chard LS, Higa T, Belsham GJ, Wagner G, Tanaka J, Pelletier J. 2006. Functional characterization of IRSEes by an inhibitor of the RNS helicase elF4A. Nat Chem Biol, 2:213-220 (30.259)

Galon J, Costes A, Sanchez-Cabo F, Kirilovsky A, Mlecnik B, Lagorce, C, Tosoline M, Camus M, Berger A, Wind P, Bruneval P, Zinzindohouse F, Cugnenc PH, Trajansoki Z, Fridman WH, Pages F. 2006. Type, density, and location of immune cells within human colorectal tumors predict clinical outcome. Science, 313(5795):1960-1964 (28.103)

Susani-Etzerodt H, Schmidinger H, Riesenhuber G, Birner-Gruenberger R, Hermetter A. 2006. A versatile library of activity-based probes for fluorescence detection and/or affinity isolation of lipolytic enzymes. Chem Phys Lipids, 144:60-68 (2.647)

Guertl B, Leuschner I, Harms D, Hoefler G. 2006. Genetic clonality is a feature unifying nephroblastomas regardless of the variety of morphological subtypes. Virchows Arch, 449:171-174. (2.082)

Schmidinger H, Hermetter A and Birner-Gruenberger R. Activity-based proteomics: Enzymatic activity profiling in complex proteomes. Amino Acids, 2006 Jun;30(4):333-50 (4.132)

Birner-Gruenberger R, Schmidinger H, Scholze H, Loidl A and Hermetter A. Fluorescent probes for lipolytic enzymes. In: Enzyme Assays and Fingerprinting, Reymond JL (ed.), Wiley-VCH, Weinheim, Germany, 241-269, 2006

Schmidinger H, Susani-Etzerodt H, Birner-Gruenberger R, and Hermetter A. Inhibitor and protein microarrays for activity-based recognition of lipolytic enzymes, Chembiochem, 7(3):527-34, 2006 Pubmed (3.322)

Tschernatsch MMO, Mlecnik B, Trajanoski Z, Zechner R, Zimmermann R. LPL-mediated lipolysis of VLDL induces an upregulation of AU-rich mRNAs and an activation of HuR in endothelial cells. Atherosclerosis, 189(2):310-317, 2006 Pubmed (4.601)

Schweiger M, Schreiber R, Haemmerle G, Lass A, Fledelius C, Jacobsen P, Tornqvist H, Zechner R, Zimmermann R. Adipose triglyceride lipase and hormone-sensitive lipase are the major enzymes in adipose tissue triacylglycerol catabolism. J Biol Chem, 281:40236-40241, 2006 (5.520)

Haemmerle G, Lass A, Zimmermann R, Gorkiewicz G, Meyer C, Rozman J, Heldmaier G, Maier R, Theussl C, Eder S, Kratky D, Wagner EF, Klingenspor M, Hoefler G, Zechner R. Defective lipolysis and altered energy metabolism in mice lacking adipose triglyceride lipase. Science, 312(5774):734-737, 2006 (free access to full paper) Pubmed (28.103)

Lass A, Zimmermann R, Haemmerle G, Riederer M, Schoiswohl G, Schweiger M, Kienesberger P, Strauss JG, Gorkiewicz G, Zechner R. Adipose triglyceride lipase-mediated lipolysis of cellular fat stores is activated by CGI-58 and defective in Chanarin-Dorfman Syndrome. Cell Metab, 3(5):309-319, 2006 Pubmed (16.107)

Kurat CF, Natter K, Petschnigg J, Wolinski H, Scheuringer K, Scholz H, Zimmermann R, Leber R, Zechner R and Kohlwein SD. Obese yeast: Triglyceride lipolysis is functionally conserved from mammals to yeast. J Biol Chem, 281: 491-500, 2006 (5.520)

Almsherqi ZA, Kohlwein SD, Deng Y. Cubic membranes: a legend beyond the Flatland of cell membrane organization. J Cell Biol, 173(6):839-844, 2006 (9.120)

Lin JP, O'Donnell CJ, Schwaiger JP, Cupples A, Lingenhel A, Hunt SC, Yang S, Kronenberg F. Association between the UGT1A1*28 allele, bilirubin levels, and coronary heart disease in the Framingham Heart Study. Circulation, 114:1476-1481, 2006 (15.595)

Lamina C, Meisinger C, Heid IM, Loewel H, Rantner B, Wolfgang W, Kronenberg F (for the KORA Study Group): Association of ankle-brachial index and plaques in the carotid and femoral arteries with cardiovascular events and total mortality in a population-based study with 13 years of follow-up. Eur Heart J, 2006 Nov;27(21):2580-7. (8.917)

Lingenhel A, Lhotta K, Neyer U, Heid IM, Rantner B, Kronenberg MF, Koenig P, Von Eckardstein A, Schober M, Dieplinger H, Kronenberg F: Role of the kidney for the metabolism of apolipoprotein A-IV: influence of the type of proteinuria. J Lipid Res, 47(9):2071-2079 Pubmed (4.409)

Kollerits B, Auinder M, Kastenbauer T, Lingenhel A, Irsigler K, Prager R, Kronenberg F. Lipoprotein(a) as a predictor of cardiovascular disease in a prospectively followed cohort of patients with type 1 diabetes. Diabetes Care, 29(7) 1661-1663, 2006 (7.349)

Stadler M, Anderwald C, Karer T, Tura A, Kastenbauer T, Auinger M, Bieglmayer C, Wagner O, Kronenberg F, Nowotny P, Pacini G, Prager R. Increased plasma amylin in type 1 diabetic patients after kidney and pancreas transplantation: A sign of impaired beta-cell function? Diabetes Care, 29(5):1031-1038, 2006 Pubmed (7.349)

Schoenborn V, Heid IM, Vollmert C, Lingenhel A, Adams TD, Hopkins PN, Illig T, Zimmermann R, Zechner R, Hunt SC, Kronenberg F. The ATGL gene is associated with free fatty acids, triglycerides, and type 2 diabetes. Diabetes, 55(5):1270-1275, 2006 (8.398)

Mackevics V, Heid IM, Wagner SA, Cip P, Doppelmayr H, Lejnieks A, Gohlke H, Ladurner G, Illig T, Iglseder B, Kronenberg F and Paulweber B. The adiponectin gene is associated with adiponectin levels but not with characteristics of the insulin resistance syndrome in healthy Caucasians. Eur J Hum Genet, 14(3):349-356, 2006 (3.925)

Heid IM, Wagner SA, Gohlke H, Iglseder B, Mueller JC, Cip P, Ladurner G, Reiter R, Stadlmayr A, Mackevics V, Illig T, Kronenberg F and Paulweber B. Genetic architecture of the APM1 gene and its influence on adiponectin plasma levels and parameters of the metabolic syndrome in 1727 healthy Caucasians. Diabetes, 55(2):375-384, 2006 (8.398)

Boes E, Fliser D, Ritz E, Koenig P, Lhotta K, Mann JFE, Mueller GA, Neyer U, Riegel W, Riegler P and Kronenberg F, for the MMKD Study Group. Apolipoprotein A-IV predicts progression of chronic kidney disease: The Mild to Moderate Kidney Disease (MMKD) Study. J Am Soc Nephrol, 17: 528-536, 2006 Pubmed (7.505)

Felt U, Fochler M, Mueller A. Sozial robuste Wissenspolitik? Analyse partizipativ orientierter Interaktionen zwischen Wissenschaft, Politik und Oeffentlichkeit imoesterreichischen Kontext. In: Buchinger, Eva, Ulrike Felt (Hg.): Technik- und Wissenschaftssoziologie in Oesterreich. Stand und Perspektiven. Sonderband der Oesterreichischen Zeitschrift fuer Soziologie, VS Verlag fuer Sozialwissenschaften, Wiesbaden S. 103-130

 

GOLD1 Publications (2005-2002)

Birner-Gruenberger R, Susani-Etzerodt H, Waldhuber M, Schmidinger H, Riesenhuber G, Rechberger G, Kollroser M, Zimmermann M, Strauss J, Laas A, Haemmerle G, Zechner R and Hermetter A. The lipolytic proteome of mouse adipose tissue. Mol Cell Proteomics, 11: 1710-1717, 2005

Schmidinger H, Birner-Gruenberger R, Riesenhuber G, Saf R, Susani-Etzerodt H and Hermetter A. Novel fluorescent phosphonic acid esters for discrimination of lipases and esterases. Chembiochem, 6:1776-1781, 2005

Hackl H, Burkard T, Sturn A, Rubio R, Schleiffer A, Tian S, Quackenbush J, Eisenhaber F, Trajanoski Z. Molecular processes during fat cell development revealed by gene expression profiling and functional annotation. Genome Biol, 6:R108, 2005

Lindegaard MLS, Olivecrona G, Christoffersen C, Kratky D, Hannibal J, Petersen BL, Zechner R, Damm P and Nielsen LB. Endothelial and lipoprotein lipases in human and mouse placenta, J Lipid Res, 46:2339-2346, 2005

Pinent M, Blade MC, Salvado MC, Arola L, Hackl H, Quackenbush J, Trajanoski Z and Ardevol A. Grape-seed derived procyanidins interfere with adipogenesis of 3T3-L1 cells at the onset of differentiation. Int J Obesity, 29:934-941, 2005 Pubmed

Mlecnik B, Scheideler M, Hackl H, Hartler J and Trajanoski Z. PathwayExplorer: web service for visualizing high-throughput expression data on biological pathways. Nucleic Acids Res, 33:W633, 2005

Jandrositz A, Petschnigg J, Zimmermann R, Natter K, Scholze H, Hermetter A, Kohlwein SD and Leber R. The lipid droplet protein Tgl1p hydrolyzes both steryl esters and triglycerides in the yeast, Saccharomyces cerevisiae. Biochim Biophys Act Mol Cell Biol L, 1735:50-58, 2005 Pubmed

Maurer M, Molidor R, Sturn A, Hartler J, Hackl H, Stocker G, Prokesch A, Scheideler M and Trajanoski Z. MARS: Microarray analysis, retrieval, and storage system. BMC Bioinformatics, 6:101, 2005

Kratky D, Zimmermann R, Wagner EM, Strauss JG, Jin W, Kostner GM, Haemmerle G, Rader DJ and Zechner R. Endothelial lipase provides an alternative pathway for FFA uptake in lipoprotein lipase-deficient mouse adipose tissue. J Clin Invest, 115:161-167, 2005

Zechner R, Strauss JG, Haemmerle G, Lass A and Zimmermann R. Lipolysis: pathway under construction. Curr Opin Lipidol, 16:333-340, 2005 Pubmed

Natter K, Leitner P, Faschinger A, Wolinski H, McCraith S, Fields S and Kohlwein SD. The spatial organization of lipid synthesis in the yeast Saccharomyces cerevisiae derived from large-scale green fluorescent protein tagging and high-resolution microscopy. Mol Cell Proteomics, 4: 662-672, 2005

Kals, M, Natter K, Thallinger G, Trajanoski Z and Kohlwein SD. YPL.db2. The yeast protein localization database. Yeast, 22: 213-218, 2005

Heid IM, Vollmert C, Hinney A, Doering A, Geller F, Loewel H, Wichmann HE, Illig T, Hebebrand J and Kronenberg F. Association of the 103I MC4R allele with decreased body mass in 7937 participants of two population-based surveys. J Med Gen, E21:1-6, 2005 Pubmed

Kronenberg F: Dyslipidemia and nephrotic syndrome: recent advances. J Renal Nutrition 15:195-203, 2005 (invited review) Pubmed

Zimmermann R*, Strauss JG*, Haemmerle G, Schoiswohl G, Birner-Gruenberger R, Riederer M, Lass A, Neuberger G, Eisenhaber F, Hermetter A and Zechner R. * equal contribution. Fat Mobilization in Adipose Tissue Is Promoted by Adipose Triglyceride Lipase (ATGL). Science, 306: 1383-1386 (free access to full paper)

Hackl H, Maurer M, Mlecnik B, Hartler J, Stocker G, Miranda-Saavedra D and Trajanoski Z. GOLD.db: Genomics of lipid-associated disorders database. BMC Genomics, 5:93, 2004

Birner-Gruenberger R, Scholze H, Faber K and Hermetter A. Identification of various lipolytic enzymes in crude porcine pancreatic lipase preparations using covalent fluorescent inhibitors. Biotechnol Bioeng, 85: 147-154, 2004

Wagner EM, Kratky D, Haemmerle G, Hrzenjak A, Kostner GM, Steyrer E and Zechner R. Defective uptake of triglyceride-associated fatty acids in adipose tissue causes the SREBP-1c-mediated induction of lipogenesis. J Lipid Res, 45: 356-365, 2004

Augustus A, Yagyu H, Haemmerle G, Bensadoun A, Vikramadithyan RK , Park SY, Kim JK, Zechner R, Goldberg IJ. Cardiac-specific knockout of lipoprotein lipase alters plasma lipoprotein triglyceride metabolism and cardiac gene expression. J Biol Chem, 279: 25050-25057, 2004

Fritz G, Wagner EM, Lindner H, Hoffmann W, Zechner R, Glatter O. Dependence of lipoprotein-lipase-catalyzed triacylglycerol hydrolysis on droplet size of synthetic monodisperse emulsions measured with static light scattering. J Colloid Interface Sci, 275: 642-648, 2004 Pubmed

Kronenberg F, Lingenhel A, Lhotta K, Rantner B, Kronenberg MF, Koenig P, Thiery J, Koch M, Von Eckardstein A, Dieplinger H. The apolipoprotein(a) size polymorphism is associated with nephrotic syndrome. Kidney Int, 65: 606-612, 2004 Pubmed

Kronenberg F, Lingenhel A, Lhotta K, Rantner B, Kronenberg MF, Koenig P, Thiery J, Koch M, Von Eckardstein A, Dieplinger H. Lipoprotein(a)- and low-density lipoprotein-derived cholesterol in nephrotic syndrome: Impact on lipid-lowering therapy? Kidney Int, 66: 348-354, 2004 Pubmed

Kronenberg F. Epidemiology, pathophysiology and therapeutic implications of lipoprotein(a) in kidney diseases. Expert Rev Cardiovasc Ther, 2: 729-743, 2004 (invited review) Pubmed

Ziouzenkova O, Perrey S, Asatryan L, Hwang J, MacNaul KL, Moller DE, Rader DJ, Sevanian A, Zechner R, Hoefler G and Plutzky J. Lipolysis of triglyceride-rich lipoproteins generates PPAR ligands: evidence for an antiinflammatory role for lipoprotein lipase. PNAS 100:2730-2735, 2003

Zimmermann R, Haemmerle G, Wagner EM, Strauss JG, Kratky D and Zechner R. Decreased fatty acid esterification compensates for the reduced lipolytic activity in hormone-sensitive lipase-deficient white adipose tissue. J Lipid Res, 44:2089-2099, 2003

Voshol PJ, Haemmerle G, Ouwens DM, Zimmermann R, Zechner R, Teusink B, Maassen JA, Havekes LM and Romijn JA. Increased hepatic insulin sensitivity together with decreased hepatic triglyceride stores in hormone-sensitive lipase-deficient mice. Endocrinology, 144: 3456-3462, 2003

Ezeh B, Haiman M, Alber HF, Kunz B, Paulweber B, Kraft HG, Weidinger F, Pachinger O, Dieplinger H, Kronenberg F. Plasma distribution of apoA-IV in patients with coronary artery disease and healthy controls. J Lipid Res, 44:1523-1529, 2003

 

If you wish to post an announcement concerning the GOLD project please contact Ms. Caroline Schober or Ms. Julia Fröhlich.

last updated 15.05.2012