Nature Medicin International Graz Symposium on Lipid and Membrane Biology in March 2012
Lipotoxicity is referred to as the anomalous uptake, generation, and activity of lipid derivatives mediating adverse, "lipotoxic" effects including dysregulation of metabolic pathways, cell- and organelle dysfunction, and cell death.
The meeting will address lipotoxicity as a pathological basis of prevalent human diseases, such as obesity, type 2 diabetes and atherosclerosis. Recent discoveries of molecular processes that can induce or prevent lipotoxicity and that are expected to contribute to the identification of valid targets for disease intervention will be discussed.
Conference Dates
March 08-10, 2012
Opening: March 08, 02:15 pm
Conference venue: Meerscheinschlössl, Mozartgasse 3, 8010 Graz, Austria
Abstract deadline: January 20, 2012
Earyl registration: until January 31, 2012
For further information and registration please take a look at the homepage. The titles for talks will go online soon. International Graz Symposium on Lipid and Membrane Biology
Nature Medicine: ATGL-mediated fat catabolism regulates cardiac mitochondrial function via the PPARa and PGC-1a and b
GOLD scientists report in Nature Medicine that lipolysis of cellular triacylglycerols by adipose triglyceride lipase (ATGL) generates essential mediator(s) involved in PPAR activation.
Hämmerle G, Moustafa T, Wölkart G, Kotzbeck P, Büttner S, Schmidt A, van de Weijer T, Hesselink M, Jäger D, Kienesberger P, Zierler K, Schreiber R, Eichmann T, Kolb D, Schweiger M, Kumari M, Eder S, Schoiswohl G, Wongsiriroj N, Pollak N, Radner FW, Preiss-Landl K, Kolbe T, Rülicke T, Pieske B, Trauner M, Lass A, Zimmermann R, Höfler G, Cinti S, Kershaw EE, Schrauwen P, Madeo F, Mayer B, and Zechner R. ATGL-mediated fat catabolism regulates cardiac mitochondrial function via the PPAR alpha and PGC-1 alpha and beta, Nature Medicine, Epub Aug 21, 2011.
Fette Signale - Fettspaltendes Enzym produziert wichtige Botenstoffe für den Energiestoffwechsel
Presseinformationen zum aktuellen Nature Medicine-Artikel auf Deutsch (Vorab-Veröffentlichung 21.8.2011 19:00)
Abnehmen unerwünscht: Grazer Wissenschafter entdecken Zusammenhang zwischen fettspaltenden Enzymen und Kachexie
Presseinformationen zum aktuellen Science-Artikel auf Deutsch (Erscheinungstermin 8.7.2011)
Press Release in English: Science Article "Adipose Triglyceride Lipase Contributes to Cancer-Associated Cachexia" (published Jul 8, 2011)